I started my PhD under the supervision of Géraldine Rauchs in September 2019. I investigate the sleep alterations occurring during ageing, and their links with memory consolidation and brain alterations. Another aim of my thesis is to better understand the effects of meditation practice on sleep quality in older adults.

I joined the team in November 2019 as a clinical research technician for the Age-Well project. I am mainly involved in data acquisition, data entry and data verification. One of my main tasks is, for example, to welcome and accompany the study participants during their examinations.

I joined the team in 2018 as a research assistant in the Age-well project, and I am now doing my PhD on the interactions between lifestyle factors (e.g., cognitive, physical and social activities) and brain markers of Alzheimer’s disease. My interest lies in understanding how modifiable factors such as environment and lifestyle impact brain structure and function, and how they can be targeted to delay cognitive decline in healthy aging as well as in neurodegenerative diseases.

Hallo! - Dutch greetings - I am a postdoctoral researcher working with dr. Eric Bui (MD) on several projects. I moved from The Netherlands and arrived in France at the beginning of 2022 to join the lab and will stay for at least 1,5 years. In my projects I will mainly focus on the effects of different interventions on symptom reductions in patients with symptoms of prolonged grief disorder and their involved underlying neural and physiological stress mechanisms (mindfulness training - CALM-NiPS pilot study; near-infrared light headband - NIRS study) by using fMRI techniques. At the same time, I am finishing up my PhD trajectory in my home country where I investigated the impact of life adversities on the vulnerability of neurobiological mechanisms underlying posttraumatic stress disorder symptomatology throughout the lifespan.

Hi ! I joined the team in 2022 for my Master's internships. Today, I hold a master's degree in neuroscience and I’m supervised by Dr Gaël Chételat. My neuroimaging work aims to study the effects of a meditation intervention on healthy older adults, compared with a non-native language training and no intervention. On the other hand, I'm trying to determine whether these effects persist in the long term. I'm using multimodal neuroimaging (such as anatomy and metabolism) to further investigate the effects of meditation on the whole brain. Meditation could be a promising approach to preserve the brain from the effects of aging.

Hi, I’m a PhD student under the supervision of Géraldine Poisnel and Gaël Chételat (UMR-S 1237). My really cool thesis project aims at understanding the impact of mental training (meditation and English learning) on the allostatic load (a cumulative measure of different blood biomarkers), an index of successful aging! I also take part in data acquisition.

I aim to disentangle the complexity of the brain changes in dementia and normal ageing and their association with behavioural and cognitive impairments. To achieve this goal, I combined PET and MRI multimodal imaging. I started my post-doctoral research at the University of Strasbourg (ICube laboratory, Integrative multimodal imaging for health Team), focusing on dementia with lewy bodies, before I relocated to the University of Sydney (Frontier Research Clinic, MIND team) where I pursued my research in Frontotemporal dementia and normal ageing. I joined Chételat’s lab in May 2021 as a postdoctoral researcher to investigate the role of dual phase PET as a biomarker of Alzheimer’s disease. With a single PET acquisition, I aim to provide a triple signature biomarker for brain perfusion, amyloid burden and white matter lesions.

Eider is interested in the neural underpinnings of normal cognition in the setting of Alzheimer’s disease. Her research notably focused on how lifestyle factors (e.g., cognitive, physical and social engagement) influence brain structure and function, relate to Alzheimer’s disease pathological processes and interact with genectic risk.

Alex joined Chételat’s Lab in 2016. His research focused on the similarities and differences in pathophysiological processes between Alzheimer’s disease and frontotemporal dementia through multimodal neuroimaging. His academic background includes a PhD at the University of Caen Normandy, under Dr. Béatrice Desgranges’s supervision, on social cognition in semantic dementia. In 2015-2016, he worked with Dr. Gil Rabinovici as a postdoctoral researcher, at University of California San Francisco (UCSF), on Tau imaging in distinct neurodegenerative disorders and longitudinal metabolic in frontotemporal dementia

My name is Victor, I’m from Le Havre and I have a Master’s degree in cellular biology. At Cyceron, I’m a research assistant in clinical research on Gaël Chételat’s team and I work on the Age-Well project. I am mainly in charge of data acquisition and data entry.

Since 2017, I am a PhD student under the supervision of Dr Gaël Chételat and the co-supervision of Pr Vincent de La Sayette. My research interest focuses on the evolution of awareness of one’s own cognitive abilities during Alzheimer’s clinical syndrome. I am interest in the brain substrates of self-awareness, its links to cognitive decline and the impact of 18-month non-pharmacological interventions based on cognitive training or meditation training on self-awareness.

Renaud initially joined the lab in 2008 for a 6-month internship, however, found himself staying involved in the lab for several years to complete both a Master’s degree and a PhD. Renaud worked extensively with high-resolution MRI data to assess hippocampal subfields, helped implement Glorbetapir-PET in the lab to measure amyloid deposition, and played with multimodal imaging to study neurodegenerative processes and their relationships to cognitive deficits. After his defence, Renaud moved to the Bay Area, where he’s been a post-doctoral fellow with Bill Jagust at UC Berkeley, and with Gil Rabinovici at UC San Francisco. In spite of the distance and time difference, Renaud has kept collaborating with Chételat’s lab on a regular basis.

Hi, her name is Inès Moulinet. She was PhD student and her project aimed at better understanding psycho-affective factors, in normal and pathological ageing (Alzheimer’s disease), using IMAP multimodal data. She also helped with the data acquisition for the Medit-Ageing project.

Justine Mutlu joined the IMAP team in 2012 to obtain her PhD. Her research work focused on better understanding the links between resting state functional connectivity and atrophy, hypometabolism and amyloid burdern in Alzheimer’s disease. The rest is not silence!

I joined the team in 2016 as a research assistant, I worked on lifestyle and neuroimaging. I also took part in data acquisition. In 2018, I started a PhD under the supervision of Géraldine Rauchs (Inserm U1077 NIMH) and I work on sleep, lifestyle and multimodal neuroimaging in the context of aging.

Audrey was working as an Engineer in the Gaël’s team from 2009 to 2015 – before having to leave for others places…She was especially involved in the IMAP project by managing and coordinating activities between the IMAP members and with associated teams.She has kept on some scientific collaborations with the team. She is particularly interested in studying subjective cognition in AD and how it changes in the course of the pathology, from the subjective cognitive decline (SCD, for more details see the SCD section of the project) at early stages, to anosognosia at later stages (MCI and AD dementia). Neuropsychology and multimodal neuroimaging from the IMAP program offer great means to address these research questions. A pretty long story with subjective memory since it was also the research topic of my PhD (University of Tours, France) and postdoc (University of California, Berkeley, US).

I have been part of the team for several years as a neuropsychologist. I take part in the passing of neuropsychological tests in the framework of research project: Silver Santé Study, a European study on aging well and sometimes on the IMAP Project (Longitudinal Study in Multimodal Imaging of Alzheimer’s Disease at an Early Stage).

Siya was a Research Engineer at Gaël’s Team. He obtained Five year integrated Master’s in Physics from the University of Mysore (India) and carried out his doctoral studies at the IMDEA ( Madrid Institute of Advanced Studies) and Universidad Autónoma de Madrid (Spain). Before joining Cyceron, he was a Research Scientist at the Neuroimaging department of the National Brain Research Centre (India). At present, he was working on the multimodal neuroimaging analysis of Alzheimer’s Disease.

Clémence has been in the lab since 2012 and obtained her doctorate degree in 2018. Her project assessed the links between brain alterations and cognition in patients with Mild Cognitive Impairment. She helped in many aspect of the 2 projects of the team :volunteer’s recruitment, data acquisition, quality check, statistical analyses and educational support for students.

Matthieu have a background in physics and biomedical engineering. He first worked as an embedded critical software architect and designer, which allowed him to complete software & system skills needed on any high complexity project. As a research engineer in neuroimaging, he improved his knowledge of PET/MRI imaging and his skills in developing imaging analysis methods in the context of neurodegenerative diseases. Eager to acquire further expertise in these fields, he did a PhD on early onset Alzheimer’s disease neuroimaging, that he obtained in December 2018, and started a Postdoctoral fellowship in Gaël Chételat’s team in February 2019. As a postdoc, he worked on the optimization of early-phase Florbetapir PET imaging as a marker of neurodegeneration.

I work as a research engineer for Age-Well. My main role is to plan, organize, and help facilitate the English learning intervention for Silver Santé Study. I am also currently writing my PhD on the subject of bilingualism and Alzheimer’s disease at the University of Paris VII Diderot. I conduct research on the psychological and cognitive effects of foreign language learning in older adults. My interests are psychoanalysis, cognitive reserve, and the psychological factors involved in learning a second language.