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Human Brains: Preserving the Brain – Forum on Neurodegenerative Diseases

Featured: Géraldine Rauchs
Oct 6, 2022

Workshop #11
Sleep in neurodegenerative diseases
Hôpital de la Pitié-Salpêtrière, Sorbonne University AP-HP, Neurology Department and Paris Brain Institute

4 October 2022 from 2.00 pm to 4.00 pm CEST

PROGRAM
Thomas Andrillon, Role of sleep in cognition and fatigue
Anne Laure Dubessy, Multiple sclerosis and sleep
Isabelle Arnulf, Parkinson’s disease and sleep
Géraldine Rauchs, Dementia and sleep (at 1:45:30)

ABSTRACT
The human brain has a major weakness: it is prone to fatigue. Recent data indicates that cognitive fatigue corresponds to the intrusion of local sleep-like patterns of neural activity in the awake brain. Plus, nighttime sleep consolidates memory. The brain damages in neurological disorders (Alzheimer disease, Parkinson’s disease and multiple sclerosis) impacts sleep and vigilance, affecting the patient’s quality of life. Conversely, altered sleep may worsen cognitive disturbances, and contribute to neurodegeneration.

YouTube video